Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Blog Article

Given the practical limitations uunipelti of solid matrix-based protocols in organoid culture, Yumiko Hirokawa et al.assess the ability of low-concentration Matrigel conditions to promote intestinal organoid growth.Their results suggest that a low-viscosity culture system can improve live cell yield compared to the existing dome method, while maintaining similar morphology, and retro doublewide represents a useful approach for high-throughput applications of organoids.